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Orbito-ocular lesions in Lagos
C C Anunobi1, F B Akinsola, F B Abdulkareem
1Department of Histopathology and Morbid Anatomy, Lagos University Teaching Hospital and the College of Medicine, University of Lagos.
The Nigerian Postgraduate Medical Journal
|October 17, 2008
Summary
This study analyzed 135 orbito-ocular lesions over 10 years, finding retinoblastoma and rhabdomyosarcoma as common childhood malignancies. Inflammatory conditions also frequently required surgical intervention.
Area of Science:
- Ophthalmology
- Pathology
- Oncology
Background:
- Orbito-ocular lesions encompass a range of conditions affecting the eye and surrounding structures.
- Understanding the epidemiology and pathology of these lesions is crucial for diagnosis and treatment.
Purpose of the Study:
- To conduct a 10-year retrospective clinicopathologic analysis of 135 orbito-ocular lesions.
- To document the patterns, sites, age, and sex distribution of these lesions.
Main Methods:
- Retrospective review of 135 orbito-ocular lesion cases.
- Analysis of slides, paraffin-embedded tissue blocks, and histology request forms.
- Data collected from the Morbid Anatomy Department of Lagos University Teaching Hospital (1994-2003).
Main Results:
- 135 samples analyzed: 75 males (56%) and 60 females (44%).
- Intraocular lesions were most common (55.5%), followed by conjunctival (20.1%), orbital (13.4%), and eyelid (11%) lesions.
- Retinoblastoma (85% of ocular malignancies) and rhabdomyosarcoma (22.2% of orbital lesions) were common childhood malignancies. Inflammatory lesions were also prevalent.
Conclusions:
- Retinoblastoma is the most frequent ocular malignancy, and rhabdomyosarcoma the most common orbital malignancy, both predominantly affecting children.
- Inflammatory orbito-ocular lesions represent a significant cause of surgical intervention in the studied population.
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