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Updated: Jun 28, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Stroke and conditions that mimic it: a protocol secures a safe early recognition
A Hatzitolios1, C Savopoulos, G Ntaios
1First Propedeutic Department of Internal Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
This study found that a specific diagnostic protocol accurately differentiated stroke from mimic conditions in 95% of elderly patients. The protocol effectively identified stroke and other serious neurological disorders, improving diagnostic accuracy.
Area of Science:
- Neurology
- Diagnostic Medicine
- Geriatrics
Background:
- Stroke is a common diagnosis in elderly patients.
- Accurate and timely differentiation between stroke and conditions that mimic it is crucial for appropriate patient management.
- Existing diagnostic protocols may not always be efficient in distinguishing stroke from similar presentations.
Purpose of the Study:
- To evaluate the effectiveness of a specialized diagnostic protocol used in a stroke unit.
- To determine the accuracy of early differentiation between stroke and mimic conditions in elderly patients.
- To assess the agreement between initial stroke diagnosis and final confirmed diagnosis.
Main Methods:
- Retrospective study of 362 elderly patients admitted with a suspected stroke diagnosis.
- Application of a comprehensive diagnostic protocol including medical history, neurological examination, vital signs, blood tests, and imaging (chest X-ray, brain CT).
- Analysis of the concordance between the initial diagnosis and the final diagnosis after applying the protocol.
Main Results:
- The diagnostic protocol achieved a 95% agreement between initial and final diagnoses.
- Of the patients studied, 95% were confirmed to have stroke (ischemic or hemorrhagic).
- The remaining 5% of patients were diagnosed with other conditions, including brain tumors (18.7% primal, 66.7% metastatic) and other diseases (18.7%).
Conclusions:
- The implemented diagnostic protocol demonstrates high efficacy in differentiating stroke from conditions with similar clinical presentations.
- The protocol ensures a high degree of diagnostic accuracy, minimizing misdiagnosis in elderly patients presenting with stroke-like symptoms.
- This approach is valuable for early and correct identification of stroke and its mimics.
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