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Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

[The assessment of heart function in children with chronic kidney disease (CKD)]

Dorota Drozdz1, Zbigniew Kordon, Jacek A Pietrzyk

  • 1Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie, Zaklad Dializ Katedry Pediatrii Polsko-Amerykańskiego Instytutu Pediatrii. dadrozdz@cm-uj.krakow.pl

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|October 18, 2008
PubMed

Insights

Children with chronic kidney disease (CKD) often show impaired diastolic cardiac function. Echocardiography can detect these cardiac changes in pediatric CKD patients.

Area of Science:

  • Pediatric Cardiology
  • Nephrology
  • Cardiovascular Research

Context:

  • Chronic kidney disease (CKD) affects children, potentially impacting cardiac health.
  • Cardiac function assessment is crucial in pediatric CKD management.
  • Echocardiography is a key non-invasive tool for evaluating cardiac structure and function.

Purpose:

  • To evaluate cardiac function using echocardiography in children diagnosed with chronic kidney disease (CKD).
  • To identify specific echocardiographic markers of cardiac dysfunction in pediatric CKD patients.

Summary:

  • The study assessed 30 children (aged 2-20) with CKD stages 2-5 using echocardiography.
  • Evaluated parameters included left ventricular (LV) dimensions, ejection fraction (EF), LV mass index (LVMI), mitral inflow velocity (E/A waves), and isovolumetric relaxation time (IRT).
  • Results indicated impaired diastolic function in 12 patients, left ventricular hypertrophy in 13, and decreased EF in 2 children with CKD stages 3-5.

Impact:

  • The findings highlight a high prevalence of diastolic dysfunction in children with CKD.
  • Echocardiography is effective in detecting cardiac abnormalities in this vulnerable pediatric population.
  • Early detection of cardiac dysfunction may inform therapeutic strategies and improve outcomes for children with CKD.
Abstract

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