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Updated: Jun 28, 2026

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction
Published on: July 18, 2025
[Pre-emptive renal transplantation in a boy with obstructive uropathy following reconstruction procedures]
Dagmara Borzych1, Iga Załuska-Leśniewska, Ilona Zagozdzon
1Klinika Chorób Nerek i Nadciśnienia Dzieci i Młodziezy AM w Gdańsku. nefped@amg.gda.pl
Abstract:
Patients with bladder dysfunction comprise over 30% of pediatric patients on renal replacement therapy. We report on a successful cadaveric pre-emptive renal transplantation performed in a boy born with posterior urethral valve. Following bilateral ureterocutaneostomies, left nephrectomy and valve resection, at 6 years of age a continent ileocolonocystoplasty was performed. The boy started intermittent daytime catheterization, passing urine both via urethra and fistula. At the age of 18 he received a renal transplant. Continuing the previous regime, at 1.5 years follow up his graft is well functioning (GFR >75 ml/min/1.73 m2) with sporadic episodes of urinary tract infection.
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