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Updated: Jun 28, 2026

Real-time Monitoring of Reactions Performed Using Continuous-flow Processing: The Preparation of 3-Acetylcoumarin as an Example
Published on: November 18, 2015
Automatic calibration for on-line process monitoring in continuous-flow systems
1Department of Analytical Ckemistry University of Córdoba Córdoba E-14004 Spain.
Abstract:
An automatic procedure for calibration in continuous-flow systems is proposed. A flow gradient unit in the sample channel, controlled via a switching valve, delivers a concentration gradient of the standard so that the standard concentration varies with time after the flow-rate gradient is started. Thus, the signal (absorbance)- concentration relationship can be determined and checked for (recalibration) as frequently as required. The procedure was applied to a simulated continuous monitoring of hydrazine in waters, as well as to specific water samples that were spiked with hydrazine at different concentrations.
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