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Automated Quantification and Analysis of Cell Counting Procedures Using ImageJ Plugins
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Comparison of two data interpretation programs in automated blood cell counters.

I Tsuda1, K Setoguchi, N Tatsumi

  • 1Department of Clinical and Laboratory Medicine Osaka City University Medical School Asahimachi Abeno Osaka 545 Japan.

The Journal of Automatic Chemistry
|January 1, 1990
PubMed
Summary

Automated blood cell counters with data interpretation programs effectively screen for abnormal specimens. These programs reduce laboratory workload by minimizing unnecessary manual cell analyses.

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Area of Science:

  • Hematology
  • Clinical Laboratory Science
  • Medical Technology

Background:

  • Automated blood cell counters are essential in clinical laboratories.
  • Accurate interpretation of cell distribution histograms is crucial for identifying abnormal specimens.
  • Manual differential counts are time-consuming and resource-intensive.

Purpose of the Study:

  • To evaluate the effectiveness of data interpretation programs in automated blood cell counters.
  • To assess the ability of these programs to screen for abnormal blood specimens.
  • To determine the impact of these programs on laboratory workload.

Main Methods:

  • Two automated blood cell counters with integrated data interpretation programs were assessed.
  • The programs analyzed size distribution histograms to classify specimens as 'normal', 'abnormal', or 'suspect'.
  • Manual differential counts were used as a reference for validation.

Main Results:

  • The data interpretation programs demonstrated high efficiency, around 90%.
  • False-negative rates for abnormal and suspect messages were below 10%.
  • The programs successfully identified specimens requiring manual re-examination.

Conclusions:

  • Automated data interpretation programs significantly aid in screening abnormal blood specimens.
  • These programs effectively reduce the need for manual observations, thereby decreasing laboratory workload.
  • The evaluated programs offer a reliable and efficient method for routine clinical laboratory use.