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Protective effects of zinc on testes of cadmium-treated rats
Dilek Burukoğlu1, Cengiz Bayçu
1Department of Histology and Embryology, Medical Faculty, Eskişehir Osmangazi University, Eskisehir, Turkey.
Bulletin of Environmental Contamination and Toxicology
|October 18, 2008
Abstract:
In this microscopic study, the toxic effects of cadmium (Cd) and the protective role of a zinc (Zn) co-treatment were investigated in the testes of the rats treated with Cd. At the dose and duration used, Cd severely damaged the seminiferous tubules and caused the degeneration and disintegration of spermatogenic cells. Leydig cells were also lost after Cd treatment. The present study showed that zinc co-treatment protected testes against toxic effects of cadmium.
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01:41Spermatogenesis
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...
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The spermatogenic cells, responsible for producing sperm, are...