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Liquid chromatographic determination of acyclovir
D Marini1, G Pollino, F Balestrieri
1Laboratorio Chimico Centrale delle Dogane, Roma.
Abstract:
An easy and precise HPLC method was developed to determine acyclovir in liophilized vials and ointments. The described procedure detects guanine which can be present in raw material as a synthetic contaminant or a degradation product. The method proved to be simple and accurate.