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Updated: Jun 28, 2026
09:17
High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
Published on: July 29, 2011
[Atrial fibrillation and the autonomous nervous system]
István Lorincz1, Zoltán Szabó, József Simkó
1Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Altalános Orvostudományi Kar Belgyógyászati Intézet, I. Belgyógyászati Klinika, Sürgosségi Orvostan Tanszék, Debrecen Nagyerdei krt. 98. Pf. 19. 4032. lorincz@internal.med.unideb.hu
Orvosi Hetilap
|October 18, 2008
Summary
The autonomic nervous system significantly influences atrial fibrillation (AF) development and persistence. Understanding autonomic reflexes and neuroablation is key for managing this arrhythmia.
Area of Science:
- Cardiology
- Neuroscience
- Electrophysiology
Context:
- Atrial fibrillation (AF) is a complex arrhythmia influenced by the autonomic nervous system (ANS).
- Autonomic tone significantly impacts AF's initiation, maintenance, and termination.
- Current understanding of the ANS-AF relationship is evolving.
Purpose:
- To review the intricate relationship between the autonomic nervous system and atrial fibrillation.
- To discuss the role of autonomic reflexes, including the baroreflex, in AF.
- To explore the autonomic effects of pulmonary vein radiofrequency catheter ablation and vagal neuroablation.
Summary:
- The ANS plays a critical role in the genesis, maintenance, and abrupt termination of AF.
- Autonomic reflexes and neuroanatomical factors are central to AF mechanisms.
- Radiofrequency catheter ablation and pharmacologic therapies are discussed in relation to autonomic modulation.
Impact:
- Provides a comprehensive overview of ANS-AF interactions for clinicians and researchers.
- Highlights the importance of autonomic modulation in AF management strategies.
- Informs therapeutic approaches, including ablation and pharmacologic interventions, by detailing autonomic mechanisms.
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