Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biliary atresia--a 25-year survey.

R Engelskirchen1, A M Holschneider, M Gharib

  • 1Kinderchirurgische Klinik des Kinderkrankenhauses der Stadt Köln.

European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [Et Al] = Zeitschrift Fur Kinderchirurgie
|June 1, 1991
PubMed
Summary

Biliary atresia treatment in 90 children showed a 30% survival rate. Surgical interventions like Kasai-Kimura hepatoporto-jejunostomy offered limited long-term biliary flow, with only one child fully recovering.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Internal Jugular Vein Entrapment: An Underrecognized Cause of Facial Pain.

European journal of neurology·2026
Same author

Bio-inspired compensatory strategies for damage to flapping robotic propulsors.

Journal of the Royal Society, Interface·2024
Same author

A dynamical model of oncotripsy by mechanical cell fatigue: selective cancer cell ablation by low-intensity pulsed ultrasound.

Proceedings. Mathematical, physical, and engineering sciences·2020
Same author

Phase I study of temsirolimus in combination with cetuximab in patients with advanced solid tumours.

European journal of cancer (Oxford, England : 1990)·2017
Same author

Shielding calculation and criticality safety analysis of spent fuel transportation cask in research reactors.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2016
Same author

Use of amniotic grafts in the repair of gastroschisis.

Pediatric surgery international·2013

Area of Science:

  • Pediatric Surgery
  • Hepatology
  • Gastroenterology

Background:

  • Biliary atresia is a severe neonatal liver disease requiring surgical intervention.
  • Treatment outcomes for biliary atresia have historically varied.
  • Long-term results of surgical procedures for biliary atresia need continuous evaluation.

Purpose of the Study:

  • To evaluate the long-term prognosis and outcomes of surgical treatments for biliary atresia in pediatric patients.
  • To assess the effectiveness of different surgical techniques, including Kasai-Kimura hepatoporto-jejunostomy.
  • To analyze survival rates and postoperative biliary flow in children treated for biliary atresia.

Main Methods:

  • Retrospective analysis of 90 children treated for biliary atresia between 1963 and 1988.

Related Experiment Videos

  • Categorization of patients based on lesion type (intrahepatic, extrahepatic, or both).
  • Review of surgical interventions including drainage operations, diagnostic laparotomy, hepato-jejunostomy, cholecystoduodenostomy, and Kasai-Kimura hepatoporto-jejunostomy.

    • Main Results:

    • Overall survival rate was 30% (27 out of 90 patients).
    • Patients with intrahepatic bile duct hypoplasia had a higher survival rate (80%).
    • Hepatoporto-jejunostomy resulted in lasting postoperative biliary flow in only 5 of 29 cases, with one child achieving full recovery.

    Conclusions:

    • Surgical interventions for biliary atresia, including Kasai-Kimura hepatoporto-jejunostomy, demonstrate limited long-term success in achieving sustained biliary flow and complete recovery.
    • Intrahepatic bile duct hypoplasia appears to be a significant prognostic factor for improved survival.
    • Further research is needed to improve surgical outcomes and long-term management of biliary atresia.