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Palliative sedation: an essential place for clinical excellence

Philip C Higgins1, Terry Altilio

  • 1Palliative Care Service, Dana Farber/Brigham & Women's Cancer Center, 44 Binney Street, SW241B, Boston, MA 02115, USA. phiggins1@parners.org

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Ethical Concerns in Healthcare:
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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...