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Related Concept Videos

Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
Reflex Activity01:08

Reflex Activity

A reflex activity is an automatic, involuntary response to specific stimuli. It is a part of our survival mechanism, designed to protect us from potential harm. For example, when a bright light suddenly shines into our eyes, we instinctively close them or look away. This is a simple reflex activity orchestrated by the nervous system without conscious thought or effort.
A reflex exam is a diagnostic procedure performed by a healthcare professional to evaluate the functionality of a patient's...
Ankle Joint01:10

Ankle Joint

The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...
Muscles of the Leg that Move the Foot and Toes01:28

Muscles of the Leg that Move the Foot and Toes

The human leg comprises an intricate system of muscles that facilitate the movement of feet and toes. Within this system, the muscles are categorized into the anterior, lateral, and posterior compartments, each with a unique set of muscles carrying out specific functions.
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles.
Indirect Motor Pathways01:22

Indirect Motor Pathways

The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...

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Related Experiment Video

Updated: Jun 28, 2026

Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability
07:52

Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability

Published on: September 18, 2020

Segmental spinal reflex adaptations associated with chronic ankle instability.

JoEllen M Sefton1, Charlie A Hicks-Little, Tricia J Hubbard

  • 1Department of Kinesiology, Auburn University, Auburn, AL 36849-5323, USA. jmsefton@auburn.edu

Archives of Physical Medicine and Rehabilitation
|October 22, 2008
PubMed
Summary
This summary is machine-generated.

Individuals with chronic ankle instability (CAI) exhibit altered spinal reflex responses. CAI patients show reduced modulation of paired reflex depression (PRD) and increased recurrent inhibition compared to healthy controls.

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Area of Science:

  • Neuroscience
  • Biomechanics
  • Orthopedics

Background:

  • Chronic ankle instability (CAI) is a prevalent condition affecting joint stability and function.
  • The role of spinal reflexes in the neuromuscular control deficits associated with CAI remains incompletely understood.

Purpose of the Study:

  • To investigate the involvement of segmental spinal reflexes in individuals with CAI.
  • To compare motoneuron pool excitability between healthy controls and participants with CAI during different stances.

Main Methods:

  • A case-control study design was employed, comparing 22 participants with CAI to 21 healthy controls.
  • Paired reflex depression (PRD) and recurrent inhibition were measured as indicators of motoneuron pool excitability.
  • Participants performed single-leg and double-leg stances to assess reflex modulation.

Main Results:

  • A significant interaction between group (CAI vs. healthy) and stance (single vs. double leg) was observed for PRD and recurrent inhibition.
  • Healthy participants demonstrated significant modulation of PRD between stances, while CAI participants did not.
  • CAI participants exhibited significantly higher levels of recurrent inhibition compared to healthy controls.

Conclusions:

  • Individuals with CAI display impaired ability to modulate PRD when transitioning from a double-leg to a single-leg stance.
  • Elevated recurrent inhibition in CAI suggests altered spinal reflex pathways contributing to instability.
  • These findings highlight the role of spinal reflex alterations in the pathophysiology of chronic ankle instability.