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Differential diagnosis of restricted diffusion confined to the cerebral cortex
F Sheerin1, P M Pretorius, D Briley
1Department of Radiology, Stoke Mandeville Hospital, UK. fintansheerin@doctors.org.uk
Abstract:
Diffusion-weighted MRI (DWI) has become increasingly widely available over recent years and is recognized as a powerful tool in neuroimaging. It is primarily used to identify acute ischaemia in patients presenting with stroke because of the improved sensitivity it offers early in the course of the disease. DWI also contributes useful diagnostic information in a range of other conditions. In this review we describe the magnetic resonance imaging (MRI) features of a number of conditions characterized by cortical diffusion restriction (CDR).
Insights
Diffusion-weighted MRI (DWI) is a key neuroimaging tool for detecting acute stroke. This review details magnetic resonance imaging (MRI) findings for conditions showing cortical diffusion restriction (CDR).
Area of Science:
- Neuroimaging
- Radiology
- Neurology
Background:
- Diffusion-weighted MRI (DWI) is increasingly utilized in neuroimaging.
- DWI offers high sensitivity for early detection of acute ischemic stroke.
- Its utility extends beyond stroke to various other neurological conditions.
Purpose of the Study:
- To review the magnetic resonance imaging (MRI) features of conditions exhibiting cortical diffusion restriction (CDR).
- To highlight the diagnostic value of DWI in non-ischemic CDR.
Main Methods:
- Literature review of studies reporting DWI findings in conditions with CDR.
- Analysis of MRI characteristics associated with CDR.
Main Results:
- DWI is crucial for identifying acute ischemic stroke.
- Cortical diffusion restriction (CDR) on DWI can indicate various pathologies beyond ischemia.
- Specific MRI features aid in differentiating causes of CDR.
Conclusions:
- DWI is a versatile neuroimaging technique with applications beyond acute stroke.
- Understanding CDR patterns on DWI is essential for accurate diagnosis of diverse neurological disorders.
- This review provides a guide to interpreting CDR in various clinical contexts.
