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Related Experiment Videos

Neurosurgery issues in oncology.

R Sawaya1

  • 1University of Texas M.D. Anderson Cancer Center, Department of Neurosurgery, Houston 77030.

Current Opinion in Oncology
|June 1, 1991
PubMed
Summary
This summary is machine-generated.

Neurosurgery advances, including stereotactic techniques and radiosurgery, improve outcomes for brain and spine tumors. Surgical resection is superior for single brain metastases compared to radiation alone.

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Area of Science:

  • Neurosurgery
  • Oncology
  • Radiosurgery

Background:

  • Central nervous system (CNS) neoplasms require advanced surgical management.
  • Significant progress has been made in skull base, spine, and stereotactic neurosurgery.
  • A national survey analyzed patterns of care for 11,185 brain tumor patients.

Purpose of the Study:

  • To review recent advances in surgical management of CNS neoplasms.
  • To highlight the efficacy of stereotactic techniques and radiosurgery.
  • To compare surgical resection with radiation therapy for brain metastases.

Main Methods:

  • Analysis of a national survey on brain tumor patient care (97% surgical).
  • Review of stereotactic-guided craniotomies and I125 seed implantation.

Related Experiment Videos

  • Evaluation of radiosurgery (Gamma-knife, LINAC) for skull base tumors and metastases.
  • Review of historical data and clinical series for meningiomas and acoustic neuromas.
  • Analysis of a series of spinal cord ependymoma cases and a randomized study on brain metastases.

    • Main Results:

    • Stereotactic-guided craniotomies enhance accuracy and reduce operative time/hospitalization.
    • Stereotactic I125 seed implantation prolongs survival for recurrent high-grade glioma (54-81 weeks).
    • Radiosurgery shows remarkable success in managing skull base tumors, acoustic neuromas, and brain metastases.
    • Spinal cord ependymoma is surgically curable, with a series showing good outcomes.
    • Surgical resection is superior to radiation therapy alone for single brain metastases.

    Conclusions:

    • Stereotactic techniques and radiosurgery represent significant advancements in neurosurgical oncology.
    • Surgical intervention remains a cornerstone in managing various CNS tumors, including metastases.
    • Further research and application of these techniques promise improved patient survival and quality of life.