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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
A real-time three-dimensional echocardiographic quantitative analysis of left atrial function in left ventricular
Mitsushige Murata1, Shiro Iwanaga, Yuichi Tamura
1Department of Laboratory Medicine, School of Medicine, Keio University, Tokyo, Japan. muratam@sc.itc.keio.ac.jp
The American Journal of Cardiology
|October 22, 2008
Summary
Left atrial (LA) volume changes measured by 3D echocardiography effectively assess left ventricular diastolic function. Lower LA ejection fraction and dilated LA volume indicate diastolic dysfunction, correlating well with established parameters.
Area of Science:
- Cardiology
- Echocardiography
- Cardiac Physiology
Background:
- Left ventricular diastolic function evaluation is crucial for hemodynamics and cardiac disease prognosis.
- Left atrial (LA) volume serves as a significant prognostic biomarker for diastolic dysfunction.
Purpose of the Study:
- To assess left ventricular diastolic function by measuring changes in LA volume.
- To utilize real-time 3-dimensional echocardiography for precise LA volume assessment.
Main Methods:
- 106 subjects categorized into four diastolic function groups based on transmitral flow patterns.
- Real-time 3-dimensional echocardiography used to measure LA volume throughout the cardiac cycle.
- Calculated LA stroke volume and LA ejection fraction, correlating them with transmitral flow and mitral annular velocity (E').
Main Results:
- LA volume indexed to body surface area was dilated in subjects with diastolic dysfunction.
- LA ejection fraction was lower in subjects with diastolic dysfunction.
- LA volume parameters and LA ejection fraction showed significant differences between groups and correlated with E/E' ratio (LA ejection fraction best, r = -0.68).
Conclusions:
- Cyclic changes in LA volume can be accurately measured using real-time 3-dimensional echocardiography.
- Measuring LA function via 3D echocardiography offers a viable alternative for assessing left ventricular diastolic function.
