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Related Experiment Video

Updated: Jun 28, 2026

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
07:26

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Published on: May 4, 2020

Fidelity versus flexibility: translating evidence-based research into practice.

Deborah J Cohen1, Benjamin F Crabtree, Rebecca S Etz

  • 1Department of Family Medicine, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Somerset, New Jersey 08873, USA. cohendj@umdnj.edu

American Journal of Preventive Medicine
|October 24, 2008
PubMed
Summary
This summary is machine-generated.

Interventions often change during implementation. Research teams are crucial for successful translation of evidence into practice by supporting adaptations and providing motivation.

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Area of Science:

  • Health Services Research
  • Translational Science
  • Implementation Science

Background:

  • Limited understanding exists regarding the process of translating research into practice.
  • This study investigated how health interventions evolve during the implementation phase.

Purpose of the Study:

  • To examine the nature and extent of changes in health interventions during implementation.
  • To identify factors influencing intervention adaptation in primary care settings.

Main Methods:

  • A qualitative analysis of data from ten health promotion interventions in primary care practices.
  • Data collection occurred from July 2005 to September 2007, using surveys, interviews, site visits, and project diaries.
  • Iterative group process used for real-time, cross-case comparison to identify intervention adaptations.

Main Results:

  • All implemented interventions required modifications, which varied by project and practice, and were often unanticipated.
  • Adaptations were made to accommodate practice circumstances, patient needs, and personnel costs.
  • Research teams significantly facilitated intervention uptake through personal influence, motivation, retraining, and instrumental support.

Conclusions:

  • Intervention changes are a common and expected part of implementation into practice settings.
  • Successful translation of evidence into practice requires acknowledging and understanding intervention adaptations.
  • Modifying research design and reporting standards is necessary to better capture implementation efforts and adaptations for quality improvement.