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Related Concept Videos

Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

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[Osteoradionecrosis and dental implants].

L Ben Slama1, W Hasni, C De Labrouhe

  • 1Service de stomatologie et de chirurgie maxillofaciale, hôpital de la Salpêtrière, 45, boulevard de l'Hôpital, 75013 Paris, France. lbenslama@mac.com

Revue De Stomatologie Et De Chirurgie Maxillo-Faciale
|October 22, 2008
PubMed
Summary
This summary is machine-generated.

This case study details bilateral osteoradionecrosis (ORN) in a patient with dental implants placed before radiation therapy (RT). It highlights RT as a risk factor for implant failure and ORN, even years after placement.

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Radiation Oncology
  • Dental Implantology

Context:

  • Osteoradionecrosis (ORN) is a serious complication following radiation therapy (RT).
  • Dental implants placed prior to RT may be at risk for delayed complications.
  • This case presents bilateral ORN in a patient with pre-existing dental implants.

Purpose:

  • To report the first documented case of bilateral osteoradionecrosis (ORN) occurring on dental implants placed before radiation therapy (RT).
  • To investigate the potential link between pre-RT dental implants and the development of ORN.
  • To emphasize radiation therapy as a risk factor for dental implant failure and subsequent ORN.

Summary:

  • A 75-year-old woman developed bilateral ORN after RT for cheek cancer, affecting dental implants placed 10-15 years prior.
  • The first ORN lesion occurred 3 months post-RT around an osteosynthesis plate, necessitating mandibular resection.
  • A second ORN lesion developed 40 months post-RT on the contralateral side due to peri-implantitis, leading to pathological fracture.

Impact:

  • This case highlights that dental implants placed before RT can be susceptible to ORN, even years after treatment.
  • It underscores the importance of considering prior dental implants in the risk assessment for ORN in patients undergoing RT.
  • The findings suggest that RT can be an unpredictable risk factor for implant failure, potentially leading to ORN.