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Updated: Jun 28, 2026

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Isolation, Culture, and Characterization of Prostate Cancer-Associated Fibroblasts
Published on: August 1, 2025
Phyllodes tumor of the prostate.
B Aguilar1, M Villalobos, M Sotomayor
1Department of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico. badavidov@hotmail.com
Urology
|October 22, 2008
Summary
A rare benign cystic Phyllodes tumor of the prostate was diagnosed in a 67-year-old man presenting with hematuria. Complete resection is crucial to prevent recurrence or malignant transformation.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Prostate tumors are uncommon, with cystic variants presenting unique diagnostic challenges.
- Phyllodes tumors, typically found in the breast, are exceptionally rare in the prostate.
Observation:
- A 67-year-old male presented with gross hematuria, a significant urinary symptom.
- Magnetic resonance imaging revealed a large (900-mL) cystic mass at the base of the prostate, causing bladder compression.
Findings:
- Histologic examination confirmed a benign cystic Phyllodes tumor of the prostate.
- This rare tumor is characterized by a proliferation of both glandular and stromal components.
Implications:
- Complete surgical resection is essential for favorable outcomes.
- Incomplete resection, regardless of tumor grade, carries risks of recurrence, metastasis, or malignant transformation into sarcoma.
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