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Genetic factors affecting susceptibility to udder pathogens
1Faculté de Médecine Vétérinaire, Université de Liège, Liège, Belgium. jdetilleux@ulg.ac.be
Veterinary Microbiology
|October 22, 2008
Summary
Identifying genetic factors for mastitis resistance in dairy cows is crucial. New traits and biological pathways are being explored for more effective genetic improvement strategies and durable resistance.
Area of Science:
- Animal Genetics
- Dairy Science
- Disease Resistance
Background:
- Genetic factors influence mastitis susceptibility in dairy cattle.
- Traditional mastitis traits include somatic cell counts and clinical cases.
- Emerging '-omics' technologies and automated milking systems offer new trait discovery.
Purpose of the Study:
- To review traits for identifying mastitis-resistant cows.
- To assess the utility of these traits for genetic improvement.
- To discuss the durability of mastitis resistance.
Main Methods:
- Literature review of genetic studies on mastitis resistance.
- Analysis of classical and novel mastitis-related traits.
- Discussion of biological mechanisms and genetic improvement strategies.
Main Results:
- Various genetic approaches, from polygenic variation to major gene detection, have been used.
- New traits like acute phase proteins and milk flow patterns provide deeper insights.
- Understanding biological pathways aids in selecting for resistance.
Conclusions:
- Novel traits and biological insights enhance the identification of resistant cows.
- Genetic improvement programs can leverage these advancements for better mastitis resistance.
- Durability of resistance, considering co-evolution and costs, is essential for long-term success.
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