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Blood Transfusion and Agglutination

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

Blood Transfusion

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Updated: Jun 28, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

[Blood requirements and transfusion practice evolution in surgery].

C Boisson¹, P Cuvillon, M Macheboeuf

¹Division anesthésie, réanimation, douleur, urgences, groupe hospitalo-universitaire Caremeau, place Professeur-Robert-Debré, Nîmes, France. christophe.boisson@chu-nimes.fr

Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine

|October 22, 2008

Summary

Blood product consumption decreased due to safety strategies but is now increasing. A multimodal approach balancing transfusion needs and risks is essential for patient safety.

Related Experiment Videos

Last Updated: Jun 28, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Area of Science:

Transfusion Medicine
Patient Blood Management

Background:

Historically, focus on transfusion hazards reduced labile blood product use.
Recent trends show an increase in blood product consumption.
Current blood saving strategies have reached their limits, risking under-transfusion.

Purpose of the Study:

To address the rising trend in blood product consumption.
To advocate for a multimodal blood management strategy.
To emphasize the need for precise blood requirement assessment.

Main Methods:

Review of historical trends in blood product consumption.
Analysis of the limitations of current blood saving strategies.
Incorporation of scientific society consensus on transfusion guidelines.
Discussion of components of multimodal blood management.

Main Results:

A decrease in labile blood product consumption was observed in the 1990s.
A reverse tendency of increasing blood product consumption is currently noted.
The risk of under-transfusion due to overly restrictive saving strategies has been identified.

Conclusions:

A multimodal blood management strategy is necessary.
Vigilance in implementing evidence-based blood saving strategies is mandatory.
Precise assessment of blood requirements is critical to avoid both over- and under-transfusion.