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Updated: Jun 28, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Non-melanocytic mimics of melanoma: part I: intraepidermal mimics
Z S Kamil1, L C B Tong, A Al Habeeb
1Department of Laboratory Medicine and Pathobiology, University of Toronto and University Health Network, Toronto, Ontario, Canada.
Abstract:
Melanoma comprises a wide range of cytological and architectural features histopathologically and hence can mimic many benign and malignant lesions of epithelial, mesenchymal and hematopoietic cell lines of differentiation. Therefore, analysis and close clinical, histological, histochemical and immunohistochemical correlation is vital in distinguishing challenging melanoma cases from their mimics. In this review, the different features of the benign, pre-malignant and malignant intraepidermal non-melanocytic tumours and tumour-like lesions that can closely mimic intraepidermal melanoma (melanoma in situ) are emphasised.
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