Related Experiment Video
Updated: Jun 28, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
Association of rs2200733 at 4q25 with atrial flutter/fibrillation diseases in an Italian population
C Viviani Anselmi1, V Novelli, R Roncarati
1Istituto Ricovero Cura Carattere Scientifico Multimedica, Milan, Italy.
Background:
Atrial fibrillation (AF) and atrial flutter (AFL) are common cardiac conduction disorders affecting many people. Recent studies on sporadic cases of AF/AFL showed a significant association of the single nucleotide polymorphism rs2200733T with the disease, suggesting a genetic factor in the development of the disease.
Objectives:
To determine the association of rs2200733 with AF/AFL derived from an Italian population sample.
Subjects:
78 patients with AF/AFL and 348 controls took part in the study.
Design:
Genetic case-control study.
Results:
The results indicate that there is a positive, significant association between the rs2200733 T allele and patients with AF/AFL of Italian origin (allelic p<0.001 with OR = 2.17).
Conclusion:
These results derived from a sample of the Italian population agree with previously reported findings from an Icelandic study, which also found that the minor allele rs2200733 was associated with AF/AFL disease.
Related Concept Videos
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Mechanism of Cardiac Arrhythmias
Dysrhythmias IV: Characteristics of Bradyarrhythmias
Dysrhythmias II: Classification of Tachyarrhythmias
Dysrhythmias III: Characteristics of Dysrhythmias

