Related Experiment Video
Updated: Jun 28, 2026

Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography
Published on: April 13, 2018
[Venous thrombosis and bowel perforation]
Hiroyuki Uetake1, Toshiaki Ishikawa, Kenichi Sugihara
1Department of Translational Oncology, Tokyo Medical and Dental Universty, Tokyo, Japan.
Abstract:
In cancer chemotherapy, serious complications including arterial and venous thrombosis and occlusion may occur, especially when bevacizumab(Bmab)is administered. Low-molecular weight heparin(LMWH)is recommended for the treatment of venous thrombosis in the guideline of Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer' by ASCO. Full-dose anticoagulation is reported to raise no risk of bleeding tendency. For a bowel perforation case, emergency operation may be required. In the treatment of such complications, wound healing delay due to Bmab administration has to be taken into account.
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