[Morphological characteristics of the pituitary-gonad system in high altitude hypoxia]

The experiments on male rats showed that their sojourn at high altitude resulted in alterations of functional relationship between the gonadotropic pituitary cells and tests. That was characterized by synthesis inhibition and hormone release by gonadotropocytes. In the testes we found impairments in the barrier function and active substance transport in sustentocytes. Intensification of destructive processes in sustentocytes, with prolongation of adaptation duration, are mediated to a greater extent by a direct destructive high altitude factors. A decrease in hormone producing function of glandulocytes as a result of destruction processes has aggravated dysharmony of the pituitary-testes system which by the end of the second month was manifested by a marked inhibition of gonadotropic cell hormone release with preservation of the synthesis high level in them.