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Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples
Published on: May 4, 2012
Identification of an anti-MRSA dihydrofolate reductase inhibitor from a diversity-oriented synthesis
Emma E Wyatt1, Warren R J D Galloway, Gemma L Thomas
1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
Chemical Communications (Cambridge, England)
|October 22, 2008
Abstract:
The screening of a diversity-oriented synthesis library followed by structure-activity relationship investigations have led to the discovery of an anti-MRSA agent which operates as an inhibitor of Staphylococcus aureus dihydrofolate reductase.
