Related Experiment Video
Updated: Aug 13, 2026

10:10
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
Rapid enhancement of transplant-mediated pupilloconstriction after elimination of competing host optic input
J D Radel1, D J Kustra, R D Lund
1Department of Neurobiology, Anatomy and Cell Science, University of Pittsburgh School of Medicine, PA 15261.
Brain Research. Developmental Brain Research
|June 21, 1991
Abstract:
Retinae transplanted over the brainstem, when directly illuminated, cause pupilloconstriction in the host eye. This occurs even when the host eye is maintained in darkness. If the host optic nerve is then severed, the transplant-mediated response is substantially augmented within 1-2 days. It is suggested that this is due to enhancement of the signal-to-noise ratio resulting from elimination of dark discharge in the host optic nerve.

