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Related Concept Videos

Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Dialysis01:15

Dialysis

Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

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Related Experiment Video

Updated: Jun 28, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

Dialysis and the elderly: an underestimated problem.

Michele Buemi1, Antonio Lacquaniti, Davide Bolignano

  • 1Chair of Nephrology, Department of Internal Medicine, University of Messina, Messina, Italy.

Kidney & Blood Pressure Research
|October 22, 2008
PubMed
Summary

Elderly patients with end-stage renal failure face complex health challenges. Peritoneal dialysis may offer advantages over hemodialysis, but careful management strategies are crucial for this growing population.

Related Experiment Videos

Last Updated: Jun 28, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

Area of Science:

  • Nephrology
  • Geriatrics

Background:

  • End-stage renal failure and uremia are increasingly prevalent in mature and elderly adults in developed countries.
  • Elderly patients with uremia often present with poor physical condition, multiple comorbidities, and polypharmacy, complicating management.
  • Socio-environmental factors and the risk of iatrogenic damage further challenge treatment approaches in this demographic.

Purpose of the Study:

  • To review the complexities of managing end-stage renal failure in elderly patients.
  • To compare the advantages and disadvantages of peritoneal dialysis versus hemodialysis for this population.
  • To highlight the need for tailored strategies in managing elderly dialysis patients.

Main Methods:

  • Literature review and synthesis of existing data on dialysis in the elderly.
  • Comparative analysis of peritoneal dialysis and hemodialysis outcomes in older adults.
  • Discussion of common complications and critical aspects of dialysis in geriatric patients.

Main Results:

  • Peritoneal dialysis offers benefits such as less hemodynamic stress and no need for vascular access, but has a high incidence of peritonitis.
  • Hemodialysis, while sometimes the only option, frequently leads to vascular access complications, morbidity, and hospitalization.
  • Elderly patients on dialysis face specific issues including vascular disease, hypotension, cardiac problems, bleeding, and amyloid arthropathy.

Conclusions:

  • Dialysis management in the elderly requires specialized attention due to unique physiological and clinical challenges.
  • Peritoneal dialysis may be preferable in some elderly patients, but careful monitoring for complications is essential.
  • Development of effective and appropriate strategies is critical to meet the needs of this aging patient population undergoing renal replacement therapy.