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Updated: Jun 28, 2026

Electrophysiological Measurements and Analysis of Nociception in Human Infants
Published on: December 20, 2011
Parent/nurse-controlled analgesia for children with developmental delay.
Michelle L Czarnecki1, Antonella S Ferrise, Kristen E Jastrowski Mano
1Jane B Pettit Pain and Palliative Care Center, Children's Hospital of Wisconsin, Milwaukee, WI 53201, USA. mczarnecki@chw.org
Parent/nurse-controlled analgesia (PNCA) offers effective pain management for children with developmental delay. This method demonstrated low pain scores and opioid use, though careful monitoring is essential for safety.
Area of Science:
- Pediatric Pain Management
- Developmental Pediatrics
- Pharmacology
Background:
- Children with developmental delay often struggle to communicate pain, increasing risks of inadequate pain assessment and management.
- While patient-controlled analgesia (PCA) is effective, not all children can operate it independently.
- Parent/nurse-controlled analgesia (PNCA) presents a potential alternative, but its safety and efficacy require further evaluation.
Purpose of the Study:
- To assess the outcomes of PNCA in pediatric patients diagnosed with developmental delay.
- To evaluate the safety and effectiveness of PNCA for this specific patient population.
Main Methods:
- A retrospective chart review of 71 children with developmental delay who received PNCA.
- Data collection focused on a 72-hour period or until PNCA discontinuation.
Main Results:
- Patients experienced low mean pain scores and required minimal opioid medication for comfort.
- Adverse events were comparable to previous PNCA studies, with oxygen therapy being an exception.
- Somnolence and respiratory depression occurred in 2.8% of patients, necessitating naloxone administration; potential causes were identified.
Conclusions:
- PNCA appears to be an effective strategy for pain control in children with developmental delay.
- Low pain scores and manageable side effects support its utility.
- Close patient monitoring and comprehensive education are critical for ensuring safe PNCA implementation.
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