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Related Concept Videos

Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...

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Updated: Jun 28, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Recurrent diverticulitis.

Giuseppe Comparato1, Francesco Di Mario,

  • 1Division of Gastroenterology, Ospedale Pietro da Saliceto, Piacenza, Italy.

Journal of Clinical Gastroenterology
|October 22, 2008
PubMed
Summary
This summary is machine-generated.

Diverticulitis, an inflammation of colonic diverticula, affects 25% of people. Current guidelines recommend surgery after two episodes, but new evidence suggests nonoperative management is safe and effective, reducing the need for colectomy.

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Published on: December 4, 2020

Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Clinical Medicine

Background:

  • Diverticulitis is a common condition affecting 25% of the population, characterized by inflamed diverticula with potential perforation.
  • Current clinical guidelines recommend elective sigmoid resection after two episodes of uncomplicated diverticulitis to prevent severe complications.
  • This recommendation is based on limited data suggesting recurrent episodes lead to complicated diverticulitis and increased mortality.

Purpose of the Study:

  • To evaluate the current guidelines for managing recurrent diverticulitis.
  • To assess the risks associated with recurrent diverticulitis versus nonoperative management.
  • To determine if elective sigmoid resection is always necessary after multiple episodes of uncomplicated diverticulitis.

Main Methods:

  • Review of existing literature and data on diverticulitis management.
  • Analysis of outcomes for patients treated nonoperatively versus those undergoing elective colectomy.
  • Evaluation of diagnostic modalities, medical therapies, and surgical techniques in recent decades.

Main Results:

  • Recent advances in diagnostics, medical therapy, and surgical techniques have improved diverticulitis outcomes.
  • Studies indicate that patients managed nonoperatively have a low risk of recurrent disease.
  • Nonoperative management appears to be a viable and safe alternative to elective colectomy for many patients.

Conclusions:

  • The assumption that recurrent diverticulitis inevitably leads to complicated disease and higher mortality is not well-supported by current data.
  • Nonoperative management strategies for diverticulitis are associated with favorable outcomes and low recurrence risk.
  • Elective sigmoid resection may not be necessary for all patients after two episodes of uncomplicated diverticulitis, challenging existing guidelines.