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Wheezing illness caused by respiratory syncytial virus and other agents

Tetsuya Yasuno1, Tsunehiro Shimizu, Yosuke Maeda

  • 1Department of Pediatrics, Kyoto City Hospital, Kyoto, Japan. tyasuno@hosp.city.kyoto.jp

Pediatrics International : Official Journal of the Japan Pediatric Society
|October 22, 2008
PubMed
Abstract

Insights

Respiratory syncytial virus (RSV) causes common infant wheezing illness, often in younger infants. However, RSV-induced wheezing is not more severe than that caused by other pathogens.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Respiratory Medicine

Background:

  • Infant wheezing illness can be caused by respiratory syncytial virus (RSV) or other agents.
  • RSV can lead to severe illness and recurrent wheezing, but its specific impact compared to other pathogens is unclear.

Purpose of the Study:

  • To investigate the severity and characteristics of infant wheezing illness caused by RSV versus other pathogens.

Main Methods:

  • Infants with initial wheezing illness were categorized into RSV-positive and RSV-negative groups.
  • Disease severity, acute symptom intensity, and recurrent wheezing susceptibility were compared between groups.

Main Results:

  • RSV was identified in 57.4% of infants; RSV-positive infants were significantly younger.
  • No significant differences were observed in hospitalization duration, persistent wheezing, or oxygen requirement between groups.
  • Gender and family history did not significantly differ between the RSV-positive and RSV-negative groups.

Conclusions:

  • RSV is a frequent cause of wheezing illness in younger infants.
  • Wheezing illness in infancy caused by RSV is not more severe than that caused by other identified pathogenic agents.

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