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Updated: Jun 28, 2026

Development of a Negative Selectable Marker for Entamoeba histolytica
Published on: December 12, 2010
Recent insights into Entamoeba development: identification of transcriptional networks associated with stage
Upinder Singh1, Gretchen M Ehrenkaufer
1Department of Microbiology and Immunology, Stanford University School of Medicine, S-143 Grant Building, 300 Pasteur Drive, Stanford, CA 94305-5107, USA. usingh@stanford.edu
Abstract:
Entamoeba histolytica is an important human pathogen and a leading parasitic cause of death globally. The parasite life cycle alternates between the trophozoite form, which is motile and causes invasive disease and the cyst stage, which is environmentally resistant and transmits infection. Understanding the triggers that initiate stage conversion is an important yet understudied area of investigation. Recent progress in dissecting the transcriptional networks that regulate E. histolytica development is outlined in this paper.
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