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Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

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Published on: April 26, 2024

Correlation between cognitive impairment and dependence in hypoxemic COPD.

Raffaele Antonelli-Incalzi¹, Andrea Corsonello, Luigi Trojano

¹University Campus Bio-Medico, Rome, Italy.

Journal of Clinical and Experimental Neuropsychology

|October 22, 2008

Summary

Cognitive function impacts daily living independence in COPD patients, but this relationship varies across severity levels. Respiratory function alone doesn't predict dependence in these individuals.

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Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

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Published on: August 18, 2023

Area of Science:

Gerontology
Neuropsychology
Pulmonology

Background:

Chronic obstructive pulmonary disease (COPD) significantly impacts patients' quality of life and daily functioning.
Cognitive impairment is increasingly recognized as a comorbidity in COPD, potentially affecting self-management and independence.
Understanding the relationship between cognitive status and functional independence is crucial for comprehensive COPD care.

Purpose of the Study:

To investigate the relationship between cognitive function levels and personal independence in activities of daily living (ADL) among stable COPD patients.
To identify specific cognitive domains and ADL limitations that best differentiate patient groups based on cognitive function.
To determine the extent to which cognitive impairment predicts functional dependence in older adults with COPD.

Main Methods:

A cohort of 149 patients with stable COPD was assessed using 11 neuropsychological tests.
Patients were categorized into three clusters (high, mid, and low cognitive function) based on neuropsychological scores.
Discriminant analysis was employed to compare personal independence in basic and instrumental activities of daily living (BADL/IADL) across cognitive clusters.

Main Results:

The pattern of BADL/IADL independence was cluster-specific for 79.2% of the high cognitive function group and 54.9% of the low cognitive function group, but only 20.8% of the mid-level group.
Self-administration of medications, continence, financial management, and dressing were key discriminators of functional independence across clusters.
No significant differences in respiratory function were observed between the cognitive clusters.

Conclusions:

In older COPD patients, functional dependence is only partially explained by cognitive impairment.
Specific ADL, such as medication management and continence, are strongly linked to cognitive status.
Disease severity indices in COPD are not reliable predictors of a patient's level of functional dependence.