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[Hypertension and pregnancy]
Martín Rosas1, Catalina Lomelí, Celso Mendoza-González
1Departamento de Cardiología Adultos III, Instituto Nacional de Cardiología, "Ignacio Chávez", (INCICH, Juan Badiano Núm. 1, Sección XVI, Tlalpan 14080, México, DF. martinrp02@yahoo.com.mx
Insights
Hypertension during pregnancy is a significant risk factor for future cardiovascular disease (CVD). Women with a history of hypertensive pregnancies require careful monitoring for CVD risk factors.
Area of Science:
- Obstetrics and Gynecology
- Cardiology
- Public Health
Context:
- Hypertension in pregnancy, including pre-eclampsia, is an under-recognized risk factor for cardiovascular disease (CVD).
- Women with a history of hypertensive pregnancies exhibit a higher risk of cardiovascular and cerebrovascular events and a less favorable CVD risk profile.
- Shared risk factors (obesity, diabetes, renal disease) and potential long-term vascular/metabolic changes link hypertensive disorders of pregnancy to later CVD.
Purpose:
- To highlight the association between hypertensive disorders of pregnancy and long-term cardiovascular disease risk.
- To emphasize the lack of specific risk-reduction interventions for women with a history of hypertensive pregnancies.
- To advocate for the inclusion of hypertensive pregnancy history in CVD risk assessments.
Summary:
- Hypertensive disorders of pregnancy are linked to an increased long-term risk of cardiovascular disease (CVD).
- This association may stem from shared risk factors or pregnancy-induced abnormalities.
- Current evidence for targeted risk-reduction interventions is limited.
Impact:
- Highlights the need for screening hypertensive disorders of pregnancy in CVD risk assessments.
- Underscores the importance of close monitoring for conventional CVD risk factors in affected women.
- Calls for adherence to evidence-based guidelines for managing these risk factors.
Abstract:
Increasing evidence indicates that hypertension in pregnancy is an under recognized risk factor for cardiovascular disease (CVD). Compared with women who have had normotensive pregnancies, those who are hypertensive during pregnancy are at greater risk of cardiovascular and cerebrovascular events and have a less favorable overall risk profile for CVD years after the affected pregnancies. One factor that might underlie this relationship is that hypertensive disorders of pregnancy (pre-eclampsia, in particular) and CVD share several common risk factors (e.g. obesity, diabetes mellitus and renal disease). Alternatively, hypertension in pregnancy could induce long-term metabolic and vascular abnormalities that might increase the overall risk of CVD later in life. In both cases, evidence regarding risk-reduction interventions specific to women who have had hypertensive pregnancies is lacking. While awaiting results of large-scale studies, hypertensive disorders of pregnancy should be screened for during assessment of a woman's overall risk profile for CVD. Women at high risk must be monitored closely for conventional risk factors that are common to both CVD and hypertensive disorders of pregnancy and treated according to current evidence-based national guidelines.
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