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Updated: Jun 28, 2026

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
Published on: September 16, 2017
[Nuclear magnetic resonance in ischemic cardiopathy]
1Departamento de Cardiología Nuclear y Tomografía Cardiaca, Instituto Nacional de Cardiología "Ignacio Chávez", INCICH, Juan Badiano Núm. 1, Colonia Sección XVI, Tlalpan 14080, México, DF.
Insights
Nuclear magnetic resonance imaging (MRI) quantifies heart function, crucial for ischemic cardiopathy prognosis. Gadolinium-enhanced MRI assesses myocardial viability and perfusion, guiding treatment decisions.
Area of Science:
- Cardiovascular Imaging
- Nuclear Magnetic Resonance Spectroscopy
- Myocardial Viability Assessment
Context:
- Ischemic cardiopathy significantly impacts prognosis, with ejection fraction being a key parameter.
- Accurate diagnosis of myocardial viability is essential for effective therapeutic strategies.
- Nuclear magnetic resonance (NMR) is the gold standard for quantifying cardiac structure and function.
Purpose:
- To detail the application of Nuclear Magnetic Resonance (NMR) techniques for assessing myocardial viability and perfusion in ischemic cardiopathy.
- To highlight the prognostic significance of ejection fraction in patients with ischemic heart disease.
- To explain the role of gadolinium contrast agents and vasodilator drugs in NMR imaging for identifying myocardial ischemia.
Summary:
- Nuclear magnetic resonance (NMR) is the gold standard for quantifying ventricular volume, ejection fraction, and myocardial mass.
- Gadolinium-enhanced NMR techniques, including first-pass and late-reinforcement, evaluate perfusion and necrotic areas.
- Vasodilators like adenosine and dipyridamole aid in identifying sub-endocardial ischemia, defining reinforcement extension from sub-endocardial to transmural compromise.
Impact:
- Provides a comprehensive overview of advanced NMR applications in ischemic cardiopathy.
- Emphasizes the critical role of accurate myocardial viability assessment in guiding patient treatment.
- Enhances understanding of how NMR imaging contributes to prognostic stratification and therapeutic planning.
Abstract:
Nuclear magnetic resonance is the "gold standard" technique to quantify the ventricular volume, the ejection fraction, and the myocardial mass. In patients suffering from ischemic cardiopathy, the ejection fraction is the most important prognostic parameter, even above from lessoned arteries index. An adequate diagnose between a non-viable and a viable myocardium is of great importance in the therapeutic approach for ischemic cardiopathy. By administrating a paramagnetic contrast media named gadolinium, fist pass and late-reinforcement techniques, are applied. With these, it is possible to evaluate the perfusion as well as necrotic areas. In order to identify sub-endocardium ischemia, drugs such as adenosine and dipiridamol, are employed as vasodilators. This technique allows the definition of reinforcement extension, being sub-endocardiac, which is an ailment which affects 50% of the myocardium depth, or even, transmural compromise.
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