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Published on: February 17, 2019
Esthesioneuroblastoma treated with external radiotherapy. Case report
F Tramacere1, S Bambace, M C De Luca
1Radiotherapy Unit, AUSL BR1, Perrino Hospital, Brindisi. francescotramacere@libero.it
Summary
Esthesioneuroblastoma, a rare nasal tumor, presents unique challenges due to its potential to invade the cranial base and orbit. This study reviews its natural history, treatment, and prognosis.
Area of Science:
- Oncology
- Otorhinolaryngology
- Neurosurgery
Background:
- Esthesioneuroblastoma is a rare intranasal cancer originating from olfactory epithelium.
- It accounts for 1-5% of all intranasal malignancies.
- The tumor frequently invades the cranial base and orbit.
Observation:
- Esthesioneuroblastoma exhibits a bimodal age distribution, with peaks in adolescence and later adulthood.
- A case report details a 79-year-old female with Kadish stage C esthesioneuroblastoma.
- Symptoms included headache, nasal obstruction, anosmia, rhinorrhoea, and epistaxis over one year.
Findings:
- The study aims to analyze the natural history, treatment, and prognosis of esthesioneuroblastoma.
- Literature review will provide insights into optimal management strategies.
- Understanding tumor behavior is crucial for improving patient outcomes.
Implications:
- This review will enhance the understanding of esthesioneuroblastoma's clinical presentation and progression.
- It will inform treatment decisions and prognostic assessments for this rare tumor.
- Further research may lead to improved diagnostic and therapeutic approaches.
