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Updated: Jun 28, 2026
05:31
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
The valve patient and pregnancy
1Cardiology Department, Bichat Hospital, Paris, France. bernard.iung@bch.aphp.fr
Expert Review of Cardiovascular Therapy
|October 23, 2008
Summary
Pregnancy increases cardiac output, posing risks for women with heart disease. Careful evaluation and specialized care are crucial for managing heart conditions during pregnancy, especially after prosthetic valve replacement.
Area of Science:
- Cardiology
- Maternal-Fetal Medicine
- Cardiovascular Disease in Pregnancy
Background:
- Pregnancy significantly increases cardiac output, which can be poorly tolerated in women with pre-existing heart conditions.
- Underlying heart disease in pregnancy requires careful management due to physiological changes.
- Prosthetic valve replacement during pregnancy presents unique challenges, particularly regarding anticoagulation.
Purpose of the Study:
- To review the impact of pregnancy on various heart diseases.
- To discuss management strategies for valvular heart disease during pregnancy.
- To highlight the complexities of anticoagulant therapy in pregnant patients with prosthetic valves.
Main Methods:
- Review of current literature on cardiovascular adaptations during pregnancy.
- Analysis of management options for valvular stenosis and regurgitation in pregnant patients.
- Discussion of risks and benefits of anticoagulation therapies (oral vs. heparin) in pregnant women with prosthetic valves.
Main Results:
- Valvular stenosis often requires intervention during pregnancy, with percutaneous intervention favored.
- Regurgitant valve diseases are generally well-tolerated during pregnancy.
- Anticoagulation in prosthetic valve recipients involves a trade-off between embryopathy risk (oral anticoagulants) and maternal thromboembolic risk (heparin).
Conclusions:
- Comprehensive pre-pregnancy cardiac evaluation is essential for women with heart disease.
- Close follow-up by specialized multidisciplinary teams is necessary for optimal outcomes.
- Individualized management plans are critical for addressing diverse cardiac conditions throughout pregnancy.
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