Metabolic syndrome in patients with ischemic heart disease
Samra Yasmin1, Nadeem Hayat Mallick, Tahir Naveed
1Department of Cardiology, Punjab Institute of Cardiology, Lahore. samarmateen4@hotmail.com
Insights
Metabolic syndrome is common in patients with Ischemic Heart Disease (IHD). This study found a high frequency of metabolic syndrome in IHD patients, highlighting the need for preventive strategies.
Area of Science:
- Cardiology
- Metabolic Disorders
- Epidemiology
Background:
- Ischemic Heart Disease (IHD) is a leading cause of mortality worldwide.
- Metabolic syndrome is a cluster of conditions that increase the risk of heart disease, stroke, and type 2 diabetes.
- Understanding the prevalence of metabolic syndrome in IHD patients is crucial for risk stratification and management.
Purpose of the Study:
- To determine the frequency of metabolic syndrome in patients diagnosed with Ischemic Heart Disease (IHD).
Main Methods:
- A cross-sectional, descriptive study was conducted.
- 100 patients with IHD were enrolled from the Punjab Institute of Cardiology.
- Data on demographic factors, metabolic syndrome components (including waist circumference, blood glucose, and lipid profiles), and diagnosis (STEMI) were collected and analyzed.
Main Results:
- The study population comprised 68% males and 32% females, with a mean age of 52 years for men and 56 years for women.
- The overall frequency of metabolic syndrome was 32% in men and 28% in women.
- Metabolic syndrome prevalence increased with age, and was notably higher in men diagnosed with STEMI (ST-elevation myocardial infarction).
Conclusions:
- A significant proportion of patients with Ischemic Heart Disease also have metabolic syndrome.
- These findings underscore the importance of screening for and managing metabolic syndrome in IHD patients.
- Preventive interventions targeting metabolic syndrome components may reduce cardiovascular risk in high-risk populations.
Objective:
To determine the frequency of metabolic syndrome in patients with Ischemic Heart Disease (IHD).
Study Design:
Cross-sectional, descriptive study.
Place And Duration Of Study:
Cardiology Department of Punjab Institute of Cardiology, Lahore, from June 2006 to June 2007.
Methodology:
A total of 100 subjects with ischemic heart disease, fulfilling the inclusion criteria, were enrolled in the study. Demographic data (age and gender) and the 5 component conditions of the metabolic syndrome were noted. Subjects were physically assessed for the abdominal obesity, based on waist circumference. Fasting blood samples for glucose and lipid profile in first 24 hours after acute coronary insult were drawn and tested in central laboratory. Variables were processed for descriptive statistics.
Results:
In this study population, 68% were male and 32% were female with mean age of 52 +/-13.6 years in men and 56 +/- 12.5 years in women. Frequency of metabolic syndrome was 32% in men and 28% in women. It increased with age. The highest rate of metabolic syndrome was in men diagnosed as STEMI (odds ratio: 3.39, 95% CI=1.36-8.41).
Conclusion:
Frequency of metabolic syndrome was high among the patients with IHD. It supports the potential for preventive efforts in persons with high-risk of IHD.
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