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Related Concept Videos

Gene-Environment Interactions01:20

Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Epigenetic Regulation01:37

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

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Related Experiment Video

Updated: Jun 28, 2026

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
10:41

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues

Published on: April 5, 2018

Epigenetics, an emerging discipline with broad implications.

Robert Feil1

  • 1Institute of Molecular Genetics, CNRS UMR-5535 and University of Montpellier, 1919 route de Mende, Montpellier, France. robert.feil@igmm.cnrs.fr

Comptes Rendus Biologies
|October 23, 2008
PubMed
Summary
This summary is machine-generated.

Epigenetics involves heritable changes in gene function without altering DNA sequence. This rapidly advancing field explores how chromatin organization influences gene expression and cellular memory, impacting development and medicine.

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Related Experiment Videos

Last Updated: Jun 28, 2026

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
10:41

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues

Published on: April 5, 2018

Epigenetic Regulation of Cardiac Differentiation of Embryonic Stem Cells and Tissues
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Epigenetic Regulation of Cardiac Differentiation of Embryonic Stem Cells and Tissues

Published on: June 3, 2016

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
10:28

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers

Published on: September 20, 2018

Area of Science:

  • Life Sciences
  • Genetics
  • Molecular Biology

Background:

  • Epigenetics is a rapidly expanding scientific field.
  • Thousands of research articles published annually explore epigenetic mechanisms.
  • Defining epigenetics remains an evolving area of study.

Purpose of the Study:

  • To review the current understanding of epigenetics and cellular memory.
  • To discuss the future direction of the epigenetics discipline.
  • To highlight the biological and medical implications of epigenetic phenomena.

Main Methods:

  • Review of recent research articles on epigenetic mechanisms.
  • Analysis of current definitions of epigenetics.
  • Discussion of findings from a scientific meeting on 'Epigenetics and Cellular Memory'.

Main Results:

  • Epigenetics involves structural organization of chromatin via modifications, proteins, and RNA.
  • These mechanisms lead to defined, perpetuatable gene expression states.
  • Epigenetic effects are crucial for development and have medical implications.

Conclusions:

  • Epigenetics encompasses heritable gene function alterations impacting development and health.
  • The field is dynamic, with ongoing refinement of its definition and scope.
  • Understanding epigenetic mechanisms is key to advancing biological and medical sciences.