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Published on: September 12, 2019
Primary ovarian Burkitt lymphoma
Andrés J Muñoz Martín1, Ricardo Pérez Fernández, M Carmen Viñuela Beneítez
1Servicio de Oncología Médica, Hospital General Universitario "Gregorio Marañón", Madrid, Spain. andresmunmar@hotmail.com
Summary
Primary ovarian Burkitt lymphoma (BL), a rare cancer, can mimic ovarian cysts. This case highlights successful chemoimmunotherapy with rituximab for a young woman diagnosed with bilateral ovarian BL.
Area of Science:
- Oncology
- Gynecologic Oncology
- Hematology
Background:
- Primary ovarian Burkitt lymphoma (BL) is an exceptionally rare non-Hodgkin lymphoma.
- It predominantly affects children and young adults, with adult presentations being exceedingly uncommon.
Observation:
- A 30-year-old woman presented with clinical features suggestive of a twisted ovarian cyst.
- Diagnostic imaging revealed bilateral ovarian masses.
Findings:
- Histopathologic examination confirmed bilateral ovarian Burkitt lymphoma.
- The patient received a treatment regimen of CODOX-M-IVAC chemotherapy combined with rituximab (an anti-CD20 monoclonal antibody).
Implications:
- This case underscores the importance of considering rare hematologic malignancies in the differential diagnosis of ovarian masses.
- Effective treatment strategies involving chemoimmunotherapy, including rituximab, can be applied to primary ovarian BL in adults.
- Further research into the optimal management of this rare entity is warranted.
