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Updated: Jun 28, 2026

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

GenBank.

Dennis A Benson¹, Ilene Karsch-Mizrachi, David J Lipman

¹National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.

Nucleic Acids Research

|October 23, 2008

Summary

This summary is machine-generated.

GenBank is a vital nucleotide sequence database covering over 300,000 organisms. It offers integrated access to diverse biological data and analysis tools through the National Center for Biotechnology Information (NCBI).

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Area of Science:

Bioinformatics
Genomics
Molecular Biology

Background:

GenBank is a major public repository for nucleotide sequences.
It encompasses data from over 300,000 organisms.
Data is sourced from individual labs and large-scale sequencing initiatives.

Purpose of the Study:

To describe the scope and accessibility of the GenBank database.
To highlight GenBank's integration with other biological resources.
To inform users about data submission and retrieval methods.

Main Methods:

Data submission via web-based BankIt or standalone Sequin programs.
Daily data synchronization with international nucleotide sequence databases (EMBL, DDBJ).
Access through the National Center for Biotechnology Information (NCBI) Entrez system.

Main Results:

GenBank provides access to over 300,000 organismal nucleotide sequences.
Integrated data includes DNA, protein, genome, and literature information.
Sequence similarity searches are facilitated by BLAST.

Conclusions:

GenBank is a comprehensive and globally coordinated resource for nucleotide sequences.
The NCBI Entrez system provides a powerful platform for data retrieval and analysis.
Regular updates and FTP access ensure data availability.