A scaffold makes the switch
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Updated: Jun 28, 2026

Electrically Conductive Scaffold to Modulate and Deliver Stem Cells
Published on: April 13, 2018
1Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599-7260, USA. henrik_dohlman@med.unc.edu
Abstract:
Protein kinase cascades are a reoccurring feature of signal transduction pathways. Recent investigations have focused on how kinase-scaffolding proteins help to convert a graded stimulus into a switch-like or binary response. New findings reveal that the graded-to-binary conversion can be turned on or off, depending on the location of the scaffold within the cell.
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