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Updated: Jun 28, 2026

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019
Tumours
Andrea Falini1, Andrea Romano, Alessandro Bozzao
1Neuroradiology Unit and CERMAC Scientific Institute and University San Raffaele, Via Olgettina 60, 20132 Milan, Italy. falini.andrea@hsr.it
Abstract:
Detection of a brain lesion is the first diagnostic step in patients with symptoms and signs suggesting the presence of a brain tumour. Imaging is primarily done to prove or rule out the presence of such a lesion. The first diagnostic evaluation is based on neuroradiological imaging, and when the diagnosis of brain tumour is highly suspicious, the type of tumour should be characterized along with its grade of malignancy, as morphological imaging alone in not specific enough to give full comprehension of brain lesions. In recent years, after continuous developments in MRI, neuroimaging has evolved into a comprehensive diagnostic tool that allows the characterization of morphological and biological alterations to diagnose and grade brain tumours and to monitor and assess treatment response and patient prognosis.
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