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The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...
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Developing a Rat Model for Bipolar Disorder
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Psychiatric diseases.

Daniele Radaelli1, Alessandro Bernasconi, Francesco Benedetti

  • 1Department of Clinical Neurosciences, Scientific Institute and University Vita-Salute, San Raffaele San Raffaele Turro, Via Stamira d'Ancona 20, 20127, Milan, Italy.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|November 15, 2008
PubMed
Summary
This summary is machine-generated.

Advances in brain imaging challenge the mind-brain divide. These techniques reveal brain abnormalities linked to psychiatric symptoms, suggesting a neural basis for mental illness.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Medical Imaging

Background:

  • Traditionally, psychiatric disorders were viewed as distinct from neurological conditions.
  • A clear boundary existed between 'diseases of the mind' and 'diseases of the brain'.

Purpose of the Study:

  • To explore how neuroimaging challenges the traditional separation of psychiatric and neurological disorders.
  • To highlight the neural underpinnings of psychiatric conditions.

Main Methods:

  • Utilizing advanced brain imaging techniques.
  • Correlating functional and structural brain abnormalities with psychopathological symptoms.

Main Results:

  • Demonstrated a link between brain abnormalities and psychiatric symptoms.
  • Provided in vivo evidence for the neural basis of psychiatric diseases.

Conclusions:

  • The distinction between psychiatric and neurological disorders is increasingly blurred.
  • Brain imaging offers a pathological anatomy for psychiatric illnesses, suggesting a neural basis.