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Related Experiment Video

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Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

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Retained appendicolith in an inflamed appendix.

Naoko Iwahashi Kondo¹, Hiroshi Kohno

¹Department of Surgery, Nagoya Ekisaikai Hospital, 4-66 Shohnen-cho, Nakagawa-ku, Nagoya 4548502, Japan. nao@med.nagoya-u.ac.jp

Emergency Radiology

|October 23, 2008

Summary

The presence of appendicolith on CT scans, especially after 10 hours of symptoms, predicts appendicitis severity. This finding aids in assessing appendicitis progression and guiding treatment decisions.

Area of Science:

Medical imaging
Gastroenterology
Surgical pathology

Background:

Risk factors for advanced appendicitis remain unclear.
Appendicitis progression requires better predictive markers.

Purpose of the Study:

To determine if appendicolith presence on CT scans correlates with appendicitis severity.
To investigate appendicolith as a predictor for advanced appendicitis.

Main Methods:

Retrospective review of 46 appendectomy patients with inflamed appendix on CT.
Patients categorized by CT scan timing: within 10 hours (Group A) vs. after 10 hours (Group B).
Correlation analysis between appendicolith detection on CT and pathological inflammatory grade.

Main Results:

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Appendicoliths detected on CT in 17 of 36 patients in Group B (scanned >10 hours).
Significant correlation found between appendicolith presence and pathological severity in Group B (p = 0.006).

Conclusions:

Appendicolith identified on CT in inflamed appendices >10 hours post-symptom onset may predict pathological grade.
This imaging finding can potentially indicate a higher risk of appendicitis progression.