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Updated: Jun 28, 2026

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
Right ventricle in congenital heart disease: is it just a "weaker" left ventricle?
1Division of Pediatric Cardiology, Columbia University, Morgan Stanley Children's Hospital of New York Presbyterian, New York, NY 10032, USA. sm364@columbia.edu
Abstract:
The RV is the dominant ventricle during fetal life. Postnatally, the RV rapidly loses its ability to sustain systemic load. In several forms of congenital heart disease, the RV is the dominant or systemic ventricle. Patients with these lesions often develop progressive RV dysfunction over time. This may be related to differences in morphology, genetic profile and hemodynamic exposure between the LV and RV. This review explores the evolutionary and developmental differences between the LV and RV, the molecular basis of these differences and the potential impact of these differences on long term RV adaptation and function in heart disease.
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