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Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy
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Adhesion design maps for fibrillar adhesives: the effect of shape

Christian Greiner1, Ralph Spolenak, Eduard Arzt

  • 1Max Planck Institute for Metals Research, Heisenbergstrasse 3, 70569 Stuttgart, Germany. greiner@mf.mpg.de

Acta Biomaterialia
|October 24, 2008
PubMed

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Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
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