Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spine Microwave Ablation: Safety and Efficacy for Treatment of Vertebral Metastases.

AJNR. American journal of neuroradiology·2022
Same author

The American Society of Neuroradiology: Cultivating a Diverse and Inclusive Culture to Build a Stronger Organization.

AJNR. American journal of neuroradiology·2021
Same author

Sodium MR Neuroimaging.

AJNR. American journal of neuroradiology·2021
Same author

Osteoid osteoma in older adults: clinical success rate of percutaneous image-guided thermal ablation.

Clinical radiology·2020
Same author

Cerebellar progressive multifocal leukoencephalopathy in a patient with a history of Crohn's disease and acute myeloid leukemia.

Acta neurologica Belgica·2019
Same author

Middle Cerebral Artery Plaque Hyperintensity on T2-Weighted Vessel Wall Imaging Is Associated with Ischemic Stroke.

AJNR. American journal of neuroradiology·2019

Related Experiment Video

Updated: Jun 28, 2026

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images
08:39

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

3D high-spatial-resolution cerebral MR venography at 3T: a contrast-dose-reduction study.

A Tomasian1, N Salamon, M S Krishnam

  • 1Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, Calif., USA. atomasian@mednet.ucla.edu

AJNR. American Journal of Neuroradiology
|October 24, 2008
PubMed
Summary

High-spatial-resolution 3D cerebral MR venography (MRV) at 3T can use reduced contrast doses. This approach maintains diagnostic image quality for most veins, with minimal impact on speed or resolution.

More Related Videos

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
10:06

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

Published on: May 10, 2012

Related Experiment Videos

Last Updated: Jun 28, 2026

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images
08:39

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
10:06

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

Published on: May 10, 2012

Area of Science:

  • Radiology
  • Neuroimaging
  • Vascular Imaging

Background:

  • Cerebral MR venography (MRV) at 3T has not been evaluated with varying contrast doses.
  • Optimizing contrast administration is crucial for diagnostic efficacy.

Purpose of the Study:

  • To compare diagnostic image quality between half-dose and full-dose contrast regimens for high-spatial-resolution 3D cerebral MRV at 3T.
  • To assess the impact of reduced contrast on venous structure definition and arterial contamination.

Main Methods:

  • Forty patients underwent 3D high-spatial-resolution cerebral contrast-enhanced MRV (CE-MRV) at 3T.
  • Patients received either a full dose (~0.1 mmol/kg) or half dose (~0.05 mmol/kg) of contrast agent.
  • Image quality, venous structure definition, arterial contamination, SNR, and CNR were evaluated.

Main Results:

  • Venous structure definition was excellent/sufficient in ~90% of segments with full dose and ~80% with half dose.
  • Delineation was significantly lower for small veins in the half-dose group (P < .01).
  • No significant difference in arterial contamination; SNR and CNR were lower with half dose (P < .01).

Conclusions:

  • High-spatial-resolution cerebral MRV at 3T can be performed with reduced contrast doses (as low as 7.5 mL).
  • Image quality is generally maintained compared to full-dose protocols, except for the smallest veins.
  • Reduced doses do not compromise acquisition speed or spatial resolution.