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Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
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[Particle size in water pipe smoke].

M-H Becquemin1, J-F Bertholon, M Attoui

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Revue Des Maladies Respiratoires
|October 24, 2008
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Summary

Narghile (water pipe) smoke contains fine particles that can be deposited in the respiratory tract. Despite water filtration, particle inhalation volume may lead to greater lung deposition than cigarette smoking.

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Area of Science:

  • Pulmonary toxicology
  • Environmental health science

Background:

  • Narghile (water pipe) smoking is widely perceived as less harmful than cigarette smoking.
  • This perception extends to both active and passive smokers.

Purpose of the Study:

  • To investigate the particle size and concentration in narghile smoke.
  • To compare the potential respiratory risks of narghile smoking versus cigarette smoking.

Main Methods:

  • Simulated narghile smoking using a sinusoidal pump.
  • Measured particle sizes and concentrations using an electrical low-pressure impactor (ELPI).
  • Analyzed particle distribution across 12 size classes (0.028–10 microm).

Main Results:

  • Narghile smoke contains microparticles and nanoparticles.
  • Water filtration reduced particle concentration by two-thirds but retained larger particles.
  • Inhaled smoke (C1) had a median particle diameter (D50) of 0.27 microm after filtration.
  • Side stream (C2) and expired (C3) smoke had smaller D50 values (0.11 and 0.25 microm, respectively).

Conclusions:

  • Particle size in filtered narghile smoke is comparable to cigarette smoke.
  • Higher inhaled volumes in narghile smoking suggest potentially greater respiratory tract deposition.
  • The popular perception of narghile being less harmful may be inaccurate due to particle deposition.