Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Parenteral Anesthetics: Overview

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.

Inhalational Anesthetics: Overview

Inhalational Anesthetics: Overview

Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...

Local Anesthetics: Clinical Application as Epidural Anesthesia

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...

Current Trends in Nursing II

Current Trends in Nursing II

Trends in nursing are multifactorial and associated with changes in society, within the nursing profession, and in other professions. Notably, telehealth and remote nursing contribute to successful healthcare delivery for numerous patients and help reduce stress for nurses due to nursing shortages. Nurses can reach patients, monitor their conditions, and interact with them using computers, audio, visual accessories, and telephones—for example, remote patient monitoring systems. Likewise,...

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...

General Anesthesia: Overview

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pediatric acute respiratory distress syndrome in children with type I - spinal muscular atrophy: a 12-year case series.

European journal of pediatrics·2025

Same author

"Glue lung": pulmonary micro-embolism caused by the glue used during interventional radiology.

BMJ case reports·2025

Same author

Transient heart stunning revealing an acute intracranial infection.

European journal of pediatrics·2025

Same author

"Evaluation of Different Inspiratory Efforts in a Pediatric Model of Healthy Lung and Pediatric Acute Respiratory Distress Syndrome During Optimized Pressure Support Ventilation and Proportional Assist Ventilation Plus (PAV+): A Bench Study.

Pediatric pulmonology·2025

Same author

Increased serum levels of proNGF, mature NGF and interleukins in burn-injured children.

European review for medical and pharmacological sciences·2024

Same author

Life-threatening complications of streptococcal sepsis: a PICU contemporary series.

Journal of anesthesia, analgesia and critical care·2023

Search research articles

Related Experiment Video

Updated: Jun 28, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

New trends in pediatric anesthesia.

D Pietrini¹, M Piastra, M Lamperti

¹Department of Anesthesiology and Intensive Care, Catholic University Medical School, Rome, Italy. d.pietrini@rm.unicatt.it

Minerva Anestesiologica

|October 24, 2008

Summary

Pediatric anesthesia has advanced with new cuffed endotracheal tubes and ultrasound guidance for central venous access and nerve blocks. Improved understanding of shock and coagulation enhances surgical and trauma care, while anesthesia depth monitoring reduces awareness.

Related Experiment Videos

Last Updated: Jun 28, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

Area of Science:

Anesthesiology
Pediatric Medicine
Surgical Innovation

Background:

Pediatric anesthesia faces challenges with invasive procedures and patient safety.
Advancements in medical technology and understanding are crucial for improving outcomes.

Purpose of the Study:

To review emerging topics and technological advancements in pediatric anesthesia.
To highlight innovations improving safety and efficacy in pediatric surgical care.

Main Methods:

Review of current literature on pediatric anesthesia innovations.
Discussion of new technologies including endotracheal tubes, ultrasound guidance, and depth of anesthesia monitoring.

Main Results:

High-volume, low-pressure cuffed endotracheal tubes mitigate stenosis risks in pediatric patients.
Ultrasound guidance enhances safety and efficacy of central venous cannulation and peripheral nerve blocks.
Improved understanding of hypovolemic shock and coagulation disorders aids management of major surgeries and trauma.
Anesthesia depth monitoring improves anesthetic control and reduces awareness incidents.

Conclusions:

Recent innovations in pediatric anesthesia contribute to safer and more effective patient care.
Technological and knowledge-based advancements are transforming pediatric surgical and trauma management.