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Related Concept Videos

Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
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Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Generation of Fluorescent Protein Fusions in Candida Species
09:27

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Published on: March 4, 2017

Congenital candidiasis.

Shwu-Meei Wang1, Chyong-Hsin Hsu, Jui-Hsing Chang

  • 1Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan. shwumeei@ms54.hinet.net

Pediatrics and Neonatology
|October 25, 2008
PubMed
Summary
This summary is machine-generated.

This study reports two newborns with congenital candidiasis presenting with skin lesions and respiratory issues. Early identification of these characteristic skin signs can aid in prompt diagnosis and treatment of this neonatal infection.

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Area of Science:

  • Neonatal Medicine
  • Dermatology
  • Infectious Diseases

Background:

  • Congenital candidiasis is a rare neonatal infection with varied clinical presentations.
  • Early diagnosis is crucial for effective management and preventing complications.

Observation:

  • Two neonates presented with diffuse erythematous papules within 24 hours of birth.
  • These skin lesions were associated with pneumonia and respiratory distress.

Findings:

  • Skin scrapings revealed Candida pseudohyphae.
  • Candida albicans was isolated from urine and sputum cultures, though systemic cultures were negative.
  • Prompt systemic antifungal therapy led to successful recovery without complications.

Implications:

  • Characteristic skin lesions can serve as early indicators of congenital candidiasis.
  • This observation aids in the timely diagnosis of neonatal candidal infections.
  • Early intervention improves patient outcomes in congenital candidiasis.